When compared with the untreated check, in both early and late production scenarios, treatment application had little to no effect on stand, color, moisture, test weight, and yield. More specifically, no statistical improvements in yield were observed as a result of any treatment applied in this study. However, a potential economic benefit was observed following a pre-plant application of ProGyp at 200 lb./a in a full-season production scenario. In this case, a numerical two bushel per acre increase over the UTC coupled with a relatively inexpensive material cost, led to a $15.60 advantage in net income. In the double-crop soybean trial, all fertilizer application treatments resulted in a net loss when compared to the UTC, but the same trend was observed regarding a full rate of ProGyp applied pre-plant. In this trial, 200 lb./a ProGyp applied pre-plant was the least detrimental to the bottom line compared to all other treatments. Interestingly, in the full-season soybean experiment, two out of five locations showed a slight numerical advantage in yield when urea was split-applied compared with urea applied up-front (TAG: +5.4bu/a; FCC: + 4.8bu/a), which may give reason to pursue this type of research further.