Farm profits are declining with increasing input costs and natural climatic issues associated with both droughts and excessive precipitation events. The ability of growers across NC to manage water stress varies depending on their geographic regions, micro-climates, soil types, infrastructure, and soybean genetics. Tools to mitigate these water losses and maintain profits are limited to variety selection (genetics), tillage, and drainage and irrigation systems. Investment and use of soil water management infrastructure to control crop moisture can only be successful with proper management and good decision-making, coupled with an excellent understanding of the agronomic potential of the varieties that are being planted. Unfortunately, varieties are constantly changing; in most cases, they are no longer commercially available after 2 to 3 years due to new genetics being introduced. This makes the quick evaluation of yield potential for new varieties under different levels of water stress highly important for growers to maximize profits at the farm level. This research and extension project will evaluate the potential yield of various new soybean varieties from multiple maturity groups to water stress extremes. In addition, the project will evaluate the final nutrient removal needs for varieties under multiple soil water scenarios. Excessive soil water, deficit soil water, and adequate soil water conditions will be considered. The ultimate goal is to provide the best data for variety placement given a producer’s ability to manage water while providing specific data on nutrient requirements given specific climate induced stress. This will promote better production economics and profits to help close the yield gap for NC producers.