2017
Effects of Soy Proteins on Bile Acid and Taurine Status in Fish
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Contributor/Checkoff:
Soy Aquaculture Alliance
Category:
Export/Trade
Keywords:
Aquaculture
Parent Project:
This is the first year of this project.
Lead Principal Investigator:
Ron Hardy, University of Idaho
Co-Principal Investigators:
Project Code:
1730-352-0504
Contributing Organization (Checkoff):
United Soybean Board
$87,411
Institution Funded:
University of Idaho
$87,411
Brief Project Summary:

This research project demonstrated that feed constituents that interfere with bile acid recycling can cause major disruption of bile acid metabolism. Results were inconclusive, as to the potential confounding effect of dietary soybean meal on taurine metabolism in fish. Soy proteins do not contain taurine, whereas animal or fish-derived feed ingredients are rich sources of taurine. Green liver disease, found in yellowtail and red sea bream, is associated with impaired bile acid metabolism, increased production of hemolytic biliverdin and reduced excretion of bile pigments from the liver into bile. This condition is corrected by dietary supplementation of taurine or bile salts.

Key Audience:
Aquaculture nutritionists, aquaculture feed producers, fish producers

Information And Results
Project Deliverables

• For the first time in fish, we will determine if soystatin, a soy protein, interferes with bile acid recycling and induces taurine deficiency. The project will identify clinical markers to quantify taurine status of fish. Soybean processors have necessary information to produce soybean proteins for aquaculture. The aquaculture industry will have information needed to formulate high-soy feeds for fish especially marine carnivores.

• This project will evaluate the performance of red drum on 12 novel, high soy protein and/or soy oil diets that will assist the industry in increasing soy inclusion in feeds.

• Development of list of specific lipids that can be supplemented to red drum feeds that allows for increased inclusion of soy oil. Through high-throughput lipid analysis this project will identity and recommend specific lipids that red drum may benefit from targeted supplementation to feeds. These will consist of lipids that are found in low concentrations in soy oil and will allow for higher usage of soy oil in feeds without losses in performance.

• Validated qPCR assays to diagnose nutritional stress. This project will further analyze and validate a set of gene expression biomarkers for nutritional stress. These assays can be utilized by fish farming, feed manufacturing, or other research groups to enhance fish and feed evaluations, especially when evaluating soy utilization.

Final Project Results

Updated February 18, 2021:

View uploaded report Word file

View uploaded report 2 PDF file

The research demonstrates that feed constituents that interfere with bile acid recycling can cause major disruption of bile acid metabolism. Results were inconclusive as to the potential confounding effect of dietary soybean meal on taurine metabolism in fish. Key takeaways show that feed constituents that interfere with bile acid recycling can cause major disruption of bile acid metabolism. Soy proteins do not contain taurine whereas animal or fish-derived feed ingredients are rich sources of taurine. Soystain did not show significant differences in impact compared to soybean meal or other diets.

The United Soybean Research Retention policy will display final reports with the project once completed but working files will be purged after three years. And financial information after seven years. All pertinent information is in the final report or if you want more information, please contact the project lead at your state soybean organization or principal investigator listed on the project.