Frogeye leaf spot (FLS) of soybean is caused by Cercospora sojina and typically affects leaves in the upper canopy. Under favorable conditions, FLS can cause up to 35% yield loss [1]. FLS is severe when soybean is grown continuously in the same field, particularly in fields where tillage is reduced, since this is a residue- and seed-borne disease. FLS was first identified in 1924 in the southeastern United States [2] and has now spread past the northern border of Nebraska and was common across the eastern third of the state in 2017[3]. Over the past few years, generic fungicides have become available to producers at a very low cost. Even though there are newer products with multiple modes...